Yes you can. There are number of ways to do that. But the most quick method is Android Emulator software. BlueStacks App Player is a free Android emulator that makes it easy to run mobile games on Windows PC.
BlueStacks: The Best Way to Play Android Games On PC
BlueStacks is just like another software which is easy to install. Just use BlueStacks like you would run MS Paint in Windows desktop. It is also known as the best emulator on PC. The BlueStacks App Player environment is very similar to that of Android device. you connect with Google Play store and install the apps and games like you normally do in any android mobile. If you got the APK file from your friends device or downloaded it from the internet, you can also install that game/app at your computer using BlueStacks. Hence, you can install any app and play android games on PC. This way you can also run e.g WhatsApp on a PC. Blustacks is an easy way to run Android Apps and games on PC. It is a free premium app for windows PC.